KCNE1 Gene
The KCNE1 gene provides instructions for making a protein that regulates the activity of potassium channels. These channels, which transport positively charged potassium atoms into and out of cells, play a key role in a cell’s ability to generate and transmit electrical signals. These channels are active in the inner ear and in cardiac muscles, where they transport potassium ions out of cells. The long QT syndrome (LQTS) is produced by mutations in the KCNE1 gene. A small percentage of cases of acquired LQTS occur in people who have an underlying mutation in the KCNE1 gene.
