ABCG5 Gene
The ABCG5 gene provides instructions for making sterolin-1, which makes up half of a protein called sterolin. Sterolin transporters in liver cells pump the plant sterols into a fluid called bile that is released into the intestine. From the intestine, the plant sterols are eliminated with the feces. Sterolin also helps regulate levels of cholesterol. Mutations in this gene may contribute to sterol accumulation and atherosclerosis.
