SCNN1B Gene
The SCNN1B gene provides instructions for making one piece, the beta subunit, of a protein complex called the epithelial sodium channel (ENaC). The channel is composed of alpha, beta, and gamma subunits, each of which is produced from a different gene. These channels are found at the surface of certain cells called epithelial cells in many tissues of the body, including the kidneys, lungs, colon, and sweat glands. Diseases associated with SCNN1B include Liddle Syndrome 1 and Bronchiectasis with or Without Elevated Sweat Chloride.
